What Causes It?
Repetitive hand movements - Especially activities involving extreme flexion or extension of the wrist, like typing, using a mouse, or manual labor.
Anatomical factors - Naturally narrow carpal tunnel or wrist fracture/dislocation that alters the space.
Sex - Women are three times more likely to develop CTS, possibly due to naturally smaller carpal tunnels.
Heredity - Family history can play a role in susceptibility to CTS.
Pregnancy - Hormonal changes and fluid retention can cause swelling in the carpal tunnel.
Inflammatory conditions - Rheumatoid arthritis and other inflammatory conditions can affect the tendons in the wrist.
Obesity - Higher body mass index is associated with increased risk.
Diabetes - Can affect the nerves, making them more susceptible to compression.
Thyroid disorders - Both hypothyroidism and hyperthyroidism can contribute to CTS.
Renal (kidney) failure - Can lead to fluid retention and nerve pressure.
Menopause - Hormonal changes may play a role.
Workplace factors - Vibrating tools, cold environments, and awkward wrist positions increase risk.
Previous wrist injuries - Sprains, strains, or fractures can alter wrist anatomy.
Signs & Symptoms
Numbness, tingling, or "pins and needles" sensation in the thumb, index, middle, and half of the ring finger.
Pain or burning in the hand and wrist that may radiate up the arm to the shoulder.
Weakened grip strength and difficulty with fine motor tasks like buttoning clothes or picking up small objects.
Tendency to drop objects due to numbness or weakness.
Symptoms that worsen at night or early morning, often waking the person from sleep.
Discomfort that may be relieved temporarily by "shaking out" the hand.
Symptoms that worsen with activities that involve flexing the wrist, like driving, reading a book, or typing.
Sensation of swelling in fingers, even without visible swelling.
In advanced cases, atrophy (wasting) of the thenar muscles at the base of the thumb.
Dry skin, swelling, or color changes in the hand due to autonomic symptoms.
Symptoms typically begin gradually and worsen over time without treatment.
In some cases, symptoms may initially come and go but eventually become more constant.
Little finger remains unaffected (an important diagnostic clue, as the median nerve doesn't supply this finger).