What Causes It?
Age (risk increases with age)
Family history and genetic factors (such as Lynch syndrome, FAP, BRCA mutations)
Personal history of inflammatory bowel disease, polyps, or other GI cancers
Lifestyle factors including smoking, alcohol consumption, and poor diet
Obesity and physical inactivity
Chronic infections (such as Hepatitis B and C for liver cancer, H. pylori for stomach cancer)
Chronic inflammation or conditions like cirrhosis, Barrett's esophagus, or pancreatitis
Environmental factors and exposure to certain chemicals or toxins
Diet high in processed or red meats and low in fruits and vegetables
Geographic and ethnic factors (certain GI cancers are more common in specific regions)
Signs & Symptoms
Persistent abdominal pain or discomfort
Unexplained weight loss
Loss of appetite or feeling full quickly
Nausea and vomiting
Changes in bowel habits (diarrhea, constipation, or narrowing of stools)
Blood in stool or black, tarry stools
Jaundice (yellowing of the skin and eyes)
Fatigue and weakness
Difficulty swallowing (especially for esophageal cancer)
Indigestion or heartburn that doesn't go away
Bloating or abdominal swelling
Pale stools and dark urine (particularly in pancreatic and liver cancers)